About 1 result found for searched term "ICA-105574 " (0.184 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M29900 | ICA-105574 | Potassium Channel |
| ICA-105574 is a potent and efficacious hERG channel activator. The primary mechanism by which ICA-105574 potentiates hERG channel activity is by removing hERG channel inactivation. ICA-105574 steeply potentiates current amplitudes more than 10-fold with an EC50 value of 0.5 +/- 0.1 μM and a Hill slope (n(H)) of 3.3 +/- 0.2. | ||
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